Toshiba Corporation, Tohoku Medical Megabank Organization (ToMMo) of Tohoku University and Tohoku University Hospital have shown that the generation of quantum cryptographic communications can provide genomic medicine with a safe and absolutely secure knowledge control environment. This was achieved by (1) creating a formula that applies quantum cryptographic communication generation to clinical sequencing, and (2) using this formula to safely convey knowledge of cancer genome research (exoma series knowledge), through an online panel of experts involving physicians and other experts. analyze serial knowledge (Figure 1). This is the first progression and demonstration in the world of a formula that uses the generation of quantum cryptographic communication in the box of genomic medicine.
Clinical sequencing is a new examination in genomic medicine that uses a next-generation seridor to read a patient’s gene series at very high speeds. The effects of genomic knowledge research are passed on to physicians and other experts to assist in patient diagnosis and selection of remedies. This formula is based on and expands the functions announced through Toshiba and ToMMo in January this year, and the achievements of this demonstration are a major step towards a practical formula that will provide a safe genomic medicine.
This study was carried out as a component of the Strategic Innovation Creation (SIP) programme of the Science and Technology and Innovation Council, “Society 5″. 0 Realization Technology Utilizing Light and Quantum”. Toshiba, ToMMo and Tohoku University Hospital will provide the main points of demonstration and generation at the QCrypt 2020 International Conference (10th International Conference on Quantum Cryptography) from August 10-14.
In January this year, Toshiba and ToMMo announced a series of quantum cryptography transmission experiments that took place in July and August 2019 and effectively conveyed knowledge of the total genome series for the first time in the world. Since then, and joined through Tohoku University Hospital, they have complex studies focusing on two spaces similar to clinical sequencing of cancer patients: knowledge to maintain confidentiality; and processes to use quantum cryptographic generation in the decryption of knowledge.
Clinical sequencing covers knowledge of genome research that are highly confidential non-public data very similar to a person’s physical condition and physical condition and should be protected. For the same reason, knowledge generated through an online panel of experts involving physicians and experts who share the patient’s genetic knowledge and diagnostic effects through remote access is also needed.
After contemplating this, Toshiba, ToMMo and Tohoku University Hospital have effectively demonstrated encryption in two spaces of quantum cryptographic communication technology:
The transmission of knowledge of genome research uses a point-in-time cryptography announced through Toshiba and ToMMo in January 2020. Genomic knowledge is encrypted as it is sequenced, with a cryptographic key distributed from the quantum key distribution formula, and transmitted to the singles pad. The transmission formula is designed to be easy to use. The menus on the operator screen allow you to simply choose the pattern number to analyze and the focus of the transmission.
A secure environment for expert panel was achieved by setting up two-way transmission of audio-visual signals that is linked to a key management server that stores and manages quantum cryptographic keys. This server receives audio-visual feeds from an on-site conferencing system, uses a one-time pad to encrypt it, and transmits it to another key management server at a different site. It uses the same one-time pad to decrypt encrypted audio-visual feeds from the other site, and transfers it to the in-house conference system. The outcome is a totally secure environment where genome data can be discussed with confidence.
Toshiba, ToMMo and Tohoku University Hospital tested this system from January to July this year. They performed a real-time transmission of 96 specimens of exome sequence data from the genomes of cancer patients of Tohoku University Hospital, and simulated a 65-minute online conference attended by a total of 10 physicians and other medical professionals. The results confirmed that quantum cryptographic communications technology supported large-scale data transfers at the genome scale, and responsive, real-time case conferencing.
These effects verify that quantum cryptographic communications enable secure knowledge transfers and real-time communications and diagnostics. In addition to providing a secure basis for genomics professionals to express and talk about highly confidential nonpublic knowledge, it also paves the way for the long-term progression of telemedicine services, where patients in remote locations can rely on the confidentiality of medical consultations. .
Demonstration base:
Toshiba Life Sciences Analysis Center (Minamiyoshinari, Aoba District, Sendai City)
Seiryo Campus of Tohoku University, construction of the tohoku medical megabank (Seiryo-machi, Aoba district, Sendai city)
Tohoku University Hospital (Seiryo-machi, Aoba Ward, Sendai City)
Period of experimentation:
January 2020 – July 2020
Transmission Information:
96 exome series knowledge samples (about 3.1 terabytes)
Knowledge of the simulated convention (approximately 1.4 gigabytes)
Number of conference participants
Ten other people in total
Toshiba will continue to work on the practical application of quantum cryptography in the major areas of security, adding medical, monetary and communications infrastructure. ToMMo and Tohoku University Hospital will continue to work hard in combination to publicize the use of secure ICT technologies for medical treatment based on genomic information.
Toshiba Corporation
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